A recent study, published in Journal of Dental Implant Research, evaluated the microbial leakage at two different implant abutment interfaces and revealed valuable insights into the striking clinical success of DSI ViruSeal.

The results proved DSI ViruSeal to be effective in controlling microbial leakage at both titanium and zirconia abutments. This material provides a reliable seal and fills the hollow spaces in the implants.

DSI ViruSeal is an antimicrobial gel, based on a viscous silicone matrix and thymol. The principle of this material is that if the place is already occupied, there will be no nutrition for vital activity of organism to grow and develop.

The purpose of the study was to determine the microbial leakage of 2 different types of organisms (Streptococcus sanguinis, Candida glabrata) in 2 groups of titanium implants (internal hexagon type of connection) with both Titanium and CAD/CAM milled Zirconia abutments. As the dimensions of these organisms are smaller, they can easily pass through the microgap in the implant abutment interface. The 2 groups were divided into two subgroups, one with DSI ViruSeal and the other without. 

All the implants were immersed in BHI broth and a poly microbial solution (S. sanguinis and Candida glabrata) was introduced. The results obtained were tabulated and statistically analysed.

On application of DSI ViruSeal both Titanium and Zirconia abutments showed statistically significant difference in microbial leakage when compared to the surface without application of the sealant for both organisms (P<0.05). 

The study concluded that DSI ViruSeal demonstrated both antibacterial and antifungal effect, irrespective of the type of abutments used. Findings indicated that application of the sealant was effective in decontaminating the implant–abutment interface and sealing the microgap.

The highly viscous silicone base ensures a reliable sealing of the implant interstitial space and prevents the ingress of organisms. The addition of thymol ensures better antifungal and antibacterial activity. The material did not get dried off, maintaining its viscosity and preventing formation of new microgaps. Thin silicone film effectively prevents adhesion of plaque on the supporting implants.

The study reported that DSI ViruSeal showed statistically significant reduction in peri-implant bacterial and fungal population compared with the interface without the sealing gel.

Click to view the study evaluating antimicrobial efficacy of DSI ViruSeal 

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